Fragile X Syndrome
Fragile X Syndrome is a chromosome abnormality that is inherited. It is the most common inherited cause of
mental impairment. Fragile X Syndrome is more common in boys occurring 1 in 3,600 while 1 in 4,000 to 6,000 girls.
Approximately 35% of children with Fragile X have Autism as well.
It is believed that between 2 and 6 percent of all children with Autism have the Fragile X gene mutation. DNA blood
tests can be taken to see if Fragile X exists in an individual.
Fragile X Syndrome has similarities to Autism symptoms such as: hand flapping, poor eye contact and short attention
span. Physical characteristics include: long faces, prominent ears and a larger head circumference. Females will
show some of these features however; these characteristics are more common in males.
Fragile X Syndrome behavior differs in males and females as well. Girls tend to be shy and they have problems with
social interaction. Depression can occur as well.
Boys tend to be easily distracted and have impulsive reactions to situations. As in Autism, there are similarities
in sensory areas such as: sensitivity to clothing, light and objects. Girls and boys both can show anxiety in
situations where their routine is broken.
Fragile X children are very loving with a wonderful sense of humor and generally like to be around people. Autism
and Fragile X are often associated with one another due to their many similar characteristics and resulting
It is important to note that no two children with Autism or Fragile X Syndrome will be alike. If you have any
concerns whether your child may have Fragile X, please see your doctor and ask him to request a DNA blood test.
If you wish to learn more about education provided to autistic children, I encourage you to visit the page
called: Autism Education.